The role of occlusion in the aetiology of temporomandibular disorders is controversial. This uncertainty may be detrimental to patients’ diagnostic procedures and treatment. To evaluate the overall evidence published on this topic, we performed a systematic review and meta-analysis of outcomes reported in articles testing the association between occlusion and clinically diagnosed TMD. For this project we teamed up with Dr. Daniele Togni, Dr. Előd Úry, Prof. Michael Kundi and Prof. Eva Piehslinger.